PTP1B inhibition and antihyperglycemic activity in the ob/ob mouse model of novel 11-arylbenzo[b]naphtho[2,3-d]furans and 11-arylbenzo[b]naphtho[2,3-d]thiophenes

MeSH terms

• Animals
• Enzyme Inhibitors / chemical synthesis*
• Enzyme Inhibitors / chemistry
• Furans / chemical synthesis*
• Furans / chemistry
• Humans
• Hypoglycemic Agents / chemical synthesis*
• Hypoglycemic Agents / chemistry
• Mice
• Mice, Obese
• Models, Molecular
• Protein Tyrosine Phosphatases / antagonists & inhibitors*
• Protein Tyrosine Phosphatases / chemistry
• Recombinant Proteins / antagonists & inhibitors
• Recombinant Proteins / chemistry
• Structure-Activity Relationship
• Thiophenes / chemical synthesis*
• Thiophenes / chemistry